Journal article 1 view
Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives
Jie Zhong 
,
Juan Mareque-Rivas ,
Xinmiao Lan ,
Yu‐Xiong Su
,
Juan Mareque-Rivas ,
Xinmiao Lan ,
Yu‐Xiong Su
Aggregate, Volume: 6, Issue: 8, Start page: e70081
Swansea University Author:
Juan Mareque-Rivas
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1002/agt2.70081
Abstract
Triterpenoids exhibit remarkable pharmacological characteristics and have garnered significant research attention, owing to their unique backbone structures and numerous modification sites. Recent advancements in supramolecular chemistry have highlighted the potential of triterpenoids to form organi...
| Published in: | Aggregate |
|---|---|
| ISSN: | 2692-4560 2692-4560 |
| Published: |
Wiley
2025
|
| Online Access: |
Check full text
|
| URI: | https://cronfa.swan.ac.uk/Record/cronfa69830 |
| Abstract: |
Triterpenoids exhibit remarkable pharmacological characteristics and have garnered significant research attention, owing to their unique backbone structures and numerous modification sites. Recent advancements in supramolecular chemistry have highlighted the potential of triterpenoids to form organized assemblies through noncovalent interactions, affording versatile functional properties. By leveraging their unique structural characteristics and biological activities, innovative strategies can be developed to enhance the efficacy and safety of biomedical therapies. This review describes the recent advances in triterpenoids serving as (i) functional groups for aggregation‐induced emission, (ii) building blocks for self‐transportation and drug delivery, (iii) potential gelators for rational hydrogel design, and (iv) cholesterol alternatives for optimizing lipid‐based nanoparticles. The biomedical perspectives of triterpenoid‐based supramolecular assemblies and potential bottlenecks in clinical translation are also discussed, with the hope of offering insights into future research and biomedical applications. |
|---|---|
| Item Description: |
Review |
| Keywords: |
hydrogels, nanotheranostics, natural products, supramolecular assembly, triterpenoids |
| College: |
Faculty of Science and Engineering |
| Funders: |
This study was supported by the National Natural Science Foundation of China (NSFC) project (32301133), the University of Hong Kong Seed Fund for Basic Research (104006533), and the R&D Program of Beijing Municipal Education Commission (KM202310025022). |
| Issue: |
8 |
| Start Page: |
e70081 |